01 - Combine smoked paprika, garlic powder, onion powder, chili powder, ground cumin, black pepper, kosher salt, and brown sugar in a small bowl.
02 - Pat brisket dry and evenly coat it with the prepared spice rub.
03 - Whisk together ketchup, apple cider vinegar, brown sugar, Worcestershire sauce, Dijon mustard, molasses, liquid smoke, beef broth, garlic powder, onion powder, black pepper, and salt until smooth.
04 - Place brisket fat side up in the slow cooker and pour BBQ sauce over it, ensuring thorough coverage.
05 - Cover and cook on low heat for 8 hours until brisket is tender.
06 - Remove brisket and allow it to rest for 10 minutes before slicing.
07 - Cut the brisket against the grain into slices or shred as desired.
08 - Skim excess fat from sauce in slow cooker and spoon sauce over the brisket when serving.